Name | (R)-(+)-Anatabine |
Synonyms | 126454-22-6 (R)-(+)-Anatabine (R)-1,2,3,6-tetrahydro-2,3'-bipyridine 2,3'-Bipyridine, 1,2,3,6-tetrahydro-, (2R)- 3-[(2R)-1,2,3,6-tetrahydropyridin-2-yl]pyridine (R)-1,2,3,6-tetrahydro-2,3'-bipyridine dihydrochloride |
CAS | 126454-22-6 |
Molecular Formula | C10H12N2 |
Molar Mass | 160.21568 |
Density | 1.045±0.06 g/cm3(Predicted) |
Boling Point | 269.0±28.0 °C(Predicted) |
pKa | 8.84±0.40(Predicted) |
biological activity | (R)-( )-Anatabine is a s-isomer of Anatabine with low activity. Anatabine is a potent α4β2 nAChR agonist. Anatabine inhibits NF-κB activation by preventing beta cleavage of the amyloid precursor protein and reduces the production of amyloid beta (Aβ). Anatabine has an anti-inflammatory effect and can be used in the study of neurodegenerative diseases. |